PROTECTIVE FACTORS FOR GASTRİC CANCER
Fruits, vegetables, and fiber:
Consumption of fruits and vegetables (particularly fruit) is probably protective against gastric cancer. Case-control studies from Europe, Asia, and North America and a pooled analysis of multiple such studies have consistently found intake of fruits and vegetables to be protective against gastric cancer, reducing the risk by approximately 30 to 40 percent for both fruits and vegetables for the highest versus lowest categories of intake.
The protection afforded by vegetables and fruits is most likely related to their vitamin C content, which is thought to reduce the formation of carcinogenic N-nitroso compounds inside the stomach. Cooked vegetables do not show the same protective effect as uncooked vegetables.
Dietary fiber may reduce the risk of gastric cancer. The association was similar for different fiber sources and types, and for diffuse type and intestinal type gastric.
NSAIDs:
Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been inversely associated with the risk of distal gastric adenocarcinoma, and there may be an interaction between NSAID use and H. pylori infection.
Reproductive hormones:
Gastric cancer incidence rates are consistently lower in women than in men in both high- and low-risk regions worldwide. There are data that support the hypothesis that reproductive hormones may have a protective role in gastric cancer risk in women.